Effects of Picamilone on learning and memory
in water and radial mazes

GV Kovalev, AG Voznesensky, VA Sazhin

[Article in Russian]

Medical Institute, 1, Pavshikh bortsov Sq.,
 Volgograd, 400066, USSR

Abstract

Picamilone in the dose of 56 mg/kg caused more pronounced nootropic effects on learning of rats in the water maze and electroshock amnesia under these conditions compared with piracetam in the dose of 200 mg/kg.  Picamilone in the dose of 10 mg/kg enhanced short-term and long-term memory in the 8 arm radial maze.  Piracetam in the dose 200 mg/kg had no effect on acquisition of rats in radial maze.
 

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